2022 MERCEDES-BENZ GLS

If you're searching for a 2022 Mercedes-Benz GLS 450 4MATIC for sale in Warren, Michigan, your search ends here. Empire Auto Collection, located in Warren in Macomb County, has this stunning blue full-size luxury SUV ready for its next owner. With seating for up to seven, a twin-turbocharged inline-six engine, and the kind of cabin refinement that rivals vehicles costing significantly more, this GLS 450 is one of the most compelling pre-owned luxury SUVs available in the Metro Detroit area right now.

About This 2022 Mercedes-Benz GLS 450 4MATIC

At 66,790 miles, this 2022 GLS 450 sits in a sweet spot for used luxury SUV buyers — past the steepest part of the depreciation curve but well within the range where Mercedes-Benz's engineering and build quality truly shine. The exterior blue finish gives this large SUV a striking, uncommon presence on the road, standing out from the typical black-and-white luxury crowd. The GLS platform was fully redesigned for the 2020 model year, meaning this 2022 example reflects the current generation's modernized design language, updated technology, and improved ride dynamics — not a dated platform.

2022 Mercedes-Benz GLS 450 Performance and Engine

Twin-Turbo Inline-Six with EQ Boost Mild Hybrid Technology

Under the hood of this GLS 450 sits a 3.0-liter turbocharged inline-six cylinder engine paired with Mercedes-Benz's proprietary EQ Boost integrated starter-generator system. This mild hybrid setup adds an electric assist layer that fills in torque at low RPM, virtually eliminating turbo lag and improving fuel efficiency without requiring a plug. The result is a smooth, effortless power delivery that makes hauling seven passengers or a full cargo load feel completely unremarkable — in the best possible way.

The 9-speed 9G-TRONIC automatic transmission is one of the smoothest-shifting gearboxes in the automotive world, and the 4MATIC all-wheel-drive system provides confident traction in Michigan winters without sacrificing the composed, boulevard-cruiser character the GLS is known for. Whether you're navigating I-696 in rush-hour traffic or heading north for a weekend in northern Michigan, this drivetrain is built for every condition Macomb County roads can throw at it.

Mercedes-Benz GLS Features and Interior

Three-Row Luxury With Technology to Match

The GLS 450 trim level puts you in a genuinely well-appointed cabin. Expect available features consistent with this generation including Mercedes-Benz's MBUX infotainment system with touchscreen and voice control, a dual-screen dashboard layout, ambient interior lighting, heated and ventilated front seats, a panoramic sunroof, and a Burmester surround sound system. The third row in the GLS is notably more accommodating than competitors — adults can actually sit back there comfortably, which is a rarity in the full-size luxury SUV segment.

Driver assistance technology on the 2022 GLS is comprehensive, with available active lane keeping assist, adaptive cruise control with stop-and-go functionality, blind spot monitoring, and a 360-degree camera system making parking this large SUV far less intimidating than its footprint suggests.

Mercedes-Benz GLS Reliability and Ownership

What Owners and Industry Data Say About the GLS Generation

The current-generation GLS (2020–present) addressed several of the reliability criticisms that followed earlier generations. Owners broadly report that the 3.0-liter turbocharged inline-six is a strong, durable engine, and the 9G-TRONIC transmission has proven dependable over time. The EQ Boost mild hybrid system adds complexity, but Mercedes-Benz has refined this technology across multiple model lines, and issues specific to this system are not commonly reported at this mileage range.

Like any European luxury vehicle, staying current with Mercedes-Benz's recommended service intervals is key — particularly oil changes using the correct specification fluid and attention to spark plugs and air filters around the 60,000-mile mark. With 66,790 miles on the clock, a prospective buyer would be smart to request service records and consider an independent pre-purchase inspection, both of which Empire Auto Collection can accommodate. Long-term owners of the GLS consistently cite ride quality, interior refinement, and the commanding driving position as reasons they stay loyal to the nameplate.

Why Buy From Empire Auto Collection in Warren, Michigan

Empire Auto Collection has built a reputation in Warren and throughout Macomb County as a trusted source for premium pre-owned vehicles. Buying a used luxury SUV is a significant decision, and working with a dealer that specializes in this segment means you're dealing with people who understand what makes a GLS 450 worth your investment — and what to look out for. The team at Empire Auto Collection is committed to a transparent, low-pressure buying experience, giving you the time and information you need to buy with confidence.

Located conveniently in Warren, Empire Auto Collection is easily accessible from across Metro Detroit, whether you're coming from the Grosse Pointes, Shelby Township, Clinton Township, or beyond. The dealership's inventory is carefully selected, and this GLS 450 is the kind of vehicle that doesn't sit on the lot long.

Financing a Used Mercedes-Benz GLS Near Warren, Michigan

Financing a pre-owned luxury vehicle doesn't have to be complicated. Empire Auto Collection works with a network of lenders to find competitive rates for buyers across a wide range of credit profiles. Whether you have excellent credit and want the lowest possible rate, or you're working to rebuild and need a lender who understands your situation, the finance team at Empire Auto Collection in Macomb County is experienced in structuring deals that make sense for real buyers.

Getting pre-approved before visiting the dealership is easy — reach out by phone at 586-662-2222 to start the conversation. Trading in your current vehicle toward the GLS 450 is also an option, and the team can walk you through current market values for your trade.

Frequently Asked Questions

Is the 2022 Mercedes-Benz GLS 450 a good buy?

Yes — the 2022 GLS 450 is widely considered one of the best full-size luxury SUVs on the market. It combines genuine three-row seating, a refined turbocharged inline-six engine, cutting-edge technology, and Mercedes-Benz's legendary interior quality at a used price point that represents strong value compared to buying new.

How many miles is too many on a used GLS 450?

With proper maintenance, the GLS 450's 3.0-liter turbo inline-six is capable of well over 150,000 miles. At 66,790 miles, this example is in the early-to-middle portion of its usable life. Buyers should verify service records and, ideally, have an independent inspection performed — standard advice for any pre-owned luxury vehicle purchase.

What does the GLS 450 trim include compared to the base GLS 580?

The GLS 450 is powered by the 3.0-liter turbocharged inline-six with EQ Boost, while the GLS 580 steps up to a biturbo V8. The 450 trim still comes generously equipped with MBUX infotainment, available air suspension, premium audio, comprehensive driver assistance features, and three-row seating — making it the more practical and affordable entry point into the GLS lineup without meaningful sacrifice in daily driving experience.

Does the 2022 GLS 450 have good reliability ratings?

The current-generation GLS has improved on the reliability reputation of its predecessors. While no European luxury vehicle is entirely maintenance-free, the 2022 GLS 450 benefits from a well-sorted engine and transmission combination, and owner satisfaction scores are consistently high for ride quality, performance, and interior technology.

Is 4MATIC all-wheel drive worth it in Michigan?

Absolutely. Michigan winters — particularly in Macomb County — can be demanding, with lake-effect snow and icy roads a regular occurrence from November through March. The 4MATIC system provides confident, intelligent all-wheel drive that distributes torque proactively, giving you traction and stability that rear-wheel-drive luxury SUVs simply can't match in local conditions.

Serving Warren and the Surrounding Macomb County Area

Empire Auto Collection proudly serves buyers from throughout Warren and the greater Macomb County region. Shoppers regularly make the trip from Sterling Heights, Clinton Township, Shelby Township, Roseville, St. Clair Shores, and communities across Oakland County and beyond to take advantage of the dealership's inventory and straightforward buying process. If you're located further out in Lapeer County or St. Clair County, the drive to Warren is well worth it for a vehicle of this caliber.

The dealership's central Warren location puts it within easy reach of major corridors including Van Dyke Avenue, Mound Road, and M-59, making it convenient no matter which direction you're coming from.

Contact Empire Auto Collection Today

Don't let this 2022 Mercedes-Benz GLS 450 4MATIC in blue slip away. Vehicles at this price point and specification move quickly, especially in a market where buyers are actively seeking this generation of GLS. Call Empire Auto Collection in Warren, Michigan at 586-662-2222 to schedule your test drive, ask about financing options, or get answers to any questions about this specific vehicle.

The team at Empire Auto Collection is ready to help you drive home in the luxury SUV you've been searching for. Stop by the dealership in Warren, in the heart of Macomb County, and experience this GLS 450 for yourself — because no description does justice to what it feels like to sit behind the wheel.